Recombinant Human Parathyroid Hormone/PTH Protein (1-84)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032854-10, PKSH032854-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: PTH
Target Synonym: Parathyroid Hormone; PTH; Parathormone; Parathyrin; PTH1
UNIProt ID: P01270
Research Areas: Signal Transduction;
Target Species: Human
Expression Host: E.coli
Fusion Tag: None
Accession: P01270
Background: Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone; parathyroid hormone-related protein; binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones; parathyroid hormone is synthesized as a preprohormone. After intracellular processing; the mature hormone is packaged within the Golgi into secretory vesicles; the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.
Sequence: Ser32-Gln115
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 9.0 kDa
Observed MW: 14 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only