Recombinant Human PMM1 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032893-10, PKSH032893-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: PMM1
Target Synonym: Phosphomannomutase 1; PMM 1; PMMH-22; PMM1; PMMH22
UNIProt ID: Q92871
Research Areas: Signal Transduction; metabolism;
Target Species: Human
Expression Host: E.coli
Fusion Tag: C-6His
Accession: Q92871
Background: Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1, 6 bisphosphate in ischemic brain.
Sequence: Met 1-Ala262
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 30.8 kDa
Observed MW: 49 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only