Recombinant Human Prolactin receptor/PRL-R Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP00128-10, RP00128-20, RP00128-50, RP00128-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human Prolactin receptor/PRL-R Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln25-Asp234) of human PRLR/Prolactin Receptor (Accession #NP_000940.1) fused with a 6×His tag at the C-terminus.
Alternate Names: HPRL, MFAB, hPRLrI, PRLR, MFAB, hPRLrI
SWISS: P16471
GeneID: 5618
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: The protenin is a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Bio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PRLR/Prolactin Receptor at 1 μg/mL (100 μL/well) can bind Prolactin Receptor Rabbit mAb with a linear range of 0.67-3.45 ng/mL.
Source: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Antigen Sequence: QLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMND
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only