Recombinant Human RAB38 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100349-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: RAB38
Target Synonym: RAB38; Ras-related protein Rab-38; Melanoma antigen NY-MEL-1
UNIProt ID: P57729
Research Areas: Signal Transduction
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
Accession: P57729
Background: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity).
Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211).
Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991).
In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
Sequence: Met 1-Ser 211
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 23.1 kDa
Observed MW: 29 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only