Recombinant Human RGMA Protein (E.coli, His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033343-10, PKSH033343-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: RGMA
Target Synonym: Repulsive guidance molecule A; RGM domain family member A; RGM
Research Areas: Neuroscience; Stem cells
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: NP_064596.2
Background: Repulsive guidance molecule A（RGMA） is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1; BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
Sequence: Pro169-Gly422
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris; 150mM NaCl; pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 29.8 kDa
Observed MW: 30 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only