Recombinant Human SEMA4B Protein (His & Fc Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033021-10, PKSH033021-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: SEMA4B
Target Synonym: Semaphorin-4B; KIAA1745; SEMAC; SEMA4B
UNIProt ID: Q9NPR2
Research Areas: Neuroscience
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Fc-6His
Accession: Q9NPR2
Background: Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain; one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
Sequence: Leu39-Glu712
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 102.0 kDa
Observed MW: 114 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only