Recombinant Human SEMA4B Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033020-10, PKSH033020-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: SEMA4B
Target Synonym: Semaphorin-4B; KIAA1745; SEMAC and SEMA4B
UNIProt ID: Q9NPR2
Research Areas: Neuroscience
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q9NPR2
Background: The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain; one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
Sequence: Leu39-Glu712
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 75.7 kDa
Observed MW: 86 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only