Recombinant Human SEMA4B Protein (His Tag) - PKSH033020

Recombinant Human SEMA4B Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH033020-10, PKSH033020-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: SEMA4B

Target Synonym: Semaphorin-4B; KIAA1745; SEMAC and SEMA4B

UNIProt ID: Q9NPR2

Research Areas: Neuroscience

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-6His

Accession: Q9NPR2

Background: The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain; one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.

Sequence: Leu39-Glu712

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 75.7 kDa

Observed MW: 86 kDa

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Research Use Only