Recombinant Human Serpin H1/HSP47 Protein
Sizes: 10ug, 50ug
Catalogue Number: RP00556-10, RP00556-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human Serpin H1/HSP47 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Ala19-Leu418) of human Heat Shock 47kDa/SERPINH1 (Accession #P50454) fused with a 6×His tag at the C-terminus.
Alternate Names: AsTP3, CBP1, CBP2, HSP47, OI10, PIG14, PPROM, RA-A47, SERPINH2, gp46, SERPINH1, CBP1, CBP2, HSP47, OI10, PIG14, PPROM, RA-A47, SERPINH2, gp46, serpin H1
SWISS: P50454
GeneID: 871
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heatshock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it isthought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to thisprotein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer andnucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm prematurerupture of membranes.
Source: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.Contact us for customized product form or formulation.
Antigen Sequence: AEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only