Recombinant Human SerpinB3/SCCA1 Protein (E.coli, His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033038-10, PKSH033038-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: SerpinB3; SCCA1
Target Synonym: Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 3; serpin peptidase inhibitor; clade B (ovalbumin); member 3; Squamous cell carcinoma antigen 1; T4-A; SCCA1; HsT1196; SCC; SCCA-1; SCCA-PD
UNIProt ID: P29508
Research Areas: Cell biology
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: P29508
Background: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Sequence: Met 1-Pro390
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 46.0 kDa
Observed MW: 40-55 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only