Recombinant Human Stathmin/STMN1 Protein
Sizes: 10ug, 50ug
Catalogue Number: RP02138-10, RP02138-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human Stathmin/STMN1 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Ala2-Asp149) of human Stathmin (Accession #P16949) fused with a 6xHis tag at the C- terminus.
Alternate Names: C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN, STMN1, LAP18, Lag, OP18, PP17, PP19, PR22, SMN, stathmin
SWISS: P16949
GeneID: 3925
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Stathmin (STMN1) is a ubiquitous cytosolic phosphoprotein which belongs to the Stathmin family. STMN1 is expressed in many tissues, with the highest expression in the brain, spinal cord, and cerebellum. It can also be expressed in the colon, ovary, placenta, uterus, and trachea. STMN1 participates in the regulation of the microtubule filament structure by destabilizing microtubules. STMN1 promotes the disassembly of microtubules and prevents assembly. STMN1 is involved in the control of the learned and innate fear. STMN1 is an intracellular relay integrating regulatory signals of the cellular environment and as an Oncoprotein in regulation of the cell cycle. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Mutation in STMN1 effects cell homeostasis that may lead to tumorigenicity.
Source: E. coli
Tag: C-His
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Contact us for customized product form or formulation.
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only