Recombinant Human SULT1A1 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033358-10, PKSH033358-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: SULT1A1
Target Synonym: Sulfotransferase 1A1; ST1A1; Aryl sulfotransferase 1; HAST1/HAST2; Phenol Sulfotransferase 1; Phenol-Sulfating Phenol Sulfotransferase 1; P-PST 1; ST1A3; Thermostable Phenol Sulfotransferase; Ts-PST; SULT1A1; STP; STP1; OK/SW-cl.88
UNIProt ID: P50225
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: P50225-1
Background: Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver; lung; adrenal; brain; platelets; and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines; phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
Sequence: Met 1-Leu295
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris; 150mM NaCl; 1mM EDTA; pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 35.5 kDa
Observed MW: 32 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only