Recombinant Human SULT1E1/ST1E1 Protein (His Tag)
Size: 50μg
Catalogue Number: PKSH031173-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: SULT1E1, ST1E1
Target Synonym: EST, EST-1, MGC34459, ST1E1, STE
Research Areas: Signal Transduction, metabolism,
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: NP_005411.1
Background: Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme which belongs to thesulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradiol. SULT1E1 maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. SULT1E1 also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations, however, cortisol, testosterone and dopamine are not sulfated. SULT1E1 is a key enzyme in estrogen homeostasis. It plays a central role in the prevention and development of human disease.
Sequence: Asn 2-Ile 294
Purity: > 92 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20mM Tris 0.5M NaCl, 20% glycerol, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 36 kDa
Observed MW: 33 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only