Recombinant Human Thioredoxin-2/MTRX/TXN2 Protein
Sizes: 10ug, 50ug
Catalogue Number: RP02177-10, RP02177-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human Thioredoxin-2/MTRX/TXN2 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Thr60-Gly166) of human TXN2 (Accession #Q99757) fused with a 6xHis tag at the N-terminus.
Alternate Names: COXPD29, MT-TRX, MTRX, TRX2, TXN, TXN2, MT-TRX, MTRX, TRX2, TXN
SWISS: Q99757
GeneID: 25828
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide, which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol- reducing activity. In addition, Thioredoxin-2 is important at low oxidative stress conditions.
Source: E. coli
Tag: N-His
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Contact us for customized product form or formulation.
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only