Recombinant Human Thioredoxin-2/TXN2 Protein (His Tag) - PKSH033109

Recombinant Human Thioredoxin-2/TXN2 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH033109-10, PKSH033109-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Thioredoxin-2; TXN2

Target Synonym: Thioredoxin Mitochondrial; MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2

UNIProt ID: Q99757

Research Areas: Signal Transduction; Cancer; metabolism;

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-6His

Accession: Q99757

Background: Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide; which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition; Thioredoxin-2 is important at low oxidative stress conditions.

Sequence: Thr60-Gly166

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 12.0 kDa

Observed MW: 13 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only