Recombinant Human TIMP-4/TIMP4 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033119-10, PKSH033119-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: TIMP-4; TIMP4
Target Synonym: Metalloproteinase inhibitor 4; TIMP-4; Tissue inhibitor of metalloproteinases 4; TIMP4
UNIProt ID: Q99727
Research Areas: Cell biology; Cardiovascular; Cancer
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q99727
Background: Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Sequence: Cys30-Pro224
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 23.5 kDa
Observed MW: 20-24 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only