Recombinant Human TIMP3 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100240-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: TIMP3
Target Synonym: HSMRK222; K222TA2; Metalloproteinase inhibitor 3; MIG 5 protein; SFD; TIMP 3; TIMP-3; Tissue Inhibitor of Metalloproteinase 3
UNIProt ID: P35625
Research Areas: Signal Transduction; Cardiovascular; Cancer; Cell Biology
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-10His
Accession: P35625
Background: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Sequence: Cys 24-Asn 144
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 13.2 kDa
Observed MW: 15 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only