Recombinant Human TLE3 Protein (aa 484-772, GST Tag)
Size: 100μg
Catalogue Number: PKSH030727-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: TLE3
Target Synonym: ESG, ESG3, GRG3, HsT18976
UNIProt ID: Q04726
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-GST
Accession: Q04726-1
Background: Immunoglobulin superfamily member 11(IGSF11) are expressed on the plasma membrane in the tesis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to over expressed in colorectal cancers and hepatocellular carcinomas as well as intestinal-type gastric cancers compared to their corresponding non- cancerous tissues. The IGSF11 has also been found expressed abundantly in testis and ovary and the IGSF11 can be used as a candidate of cancer-testis antigen.
Sequence: Ser 484-Tyr 772
Purity: > 78 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20mM Tris, 0.15M NaCl, 5mM GSH, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 58.5 kDa
Observed MW: 58.5 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only