Product Description

Recombinant Human Trefoil Factor 2/TFF2 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH033142-10, PKSH033142-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Trefoil Factor 2; TFF2

Target Synonym: Trefoil Factor 2; Spasmolysin; Spasmolytic Polypeptide; SP; TFF2; SML1

UNIProt ID: Q03403

Research Areas: Cell biology

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-6His

Accession: Q03403

Background: Trefoil Factor 2 (TFF2) is a member of the trefoil family and contains two P-type (trefoil) domains. Members of this family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF2 is a secreted protein and specifically expressed in the stomach. TFF2 inhibits gastrointestinal motility and gastric acid secretion. TFF2 could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.

Sequence: Gln24-Tyr129

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 13.0 kDa

Observed MW: 19 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only