Recombinant Human TYRO3 Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP00203-10, RP00203-20, RP00203-50, RP00203-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human TYRO3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala41-Ser428) of human Tyro3/Dtk (Accession #NP_006284.2) fused with an Fc, 6×His tag at the C-terminus.
Alternate Names: BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif, TYRO3, Dtk, Etk-2, RSE, Rek, Sky, Tif
SWISS: Q06418
GeneID: 7301
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: TYRO3, also known as Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken c-Eyk) constitute a new receptor tyrosine kinase subfamily. TYRO3 protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. TYRO3 has also been identified as a cell entry factor for Ebola and Marburg viruses.
Bio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human Gas6 at 2 μg/mL (100 μL/well) can bind Human TYRO3 with a linear range of 0.1-5.6 ng/mL.
Source: HEK293 cells
Tag: C-hFc&His
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Antigen Sequence: AGLKLMGAPVKLTVSQGQPVKLNCSVEGMEEPDIQWVKDGAVVQNLDQLYIPVSEQHWIGFLSLKSVERSDAGRYWCQVEDGGETEISQPVWLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVGPPEPVTIVWWRGTTKIGGPAPSPSVLNVTGVTQSTMFSCEAHNLKGLASSRTATVHLQALPAAPFNITVTKLSSSNASVAWMPGADGRALLQSCTVQVTQAPGGWEVLAVVVPVPPFTCLLRDLVPATNYSLRVRCANALGPSPYADWVPFQTKGLAPASAPQNLHAIRTDSGLILEWEEVIPEAPLEGPLGPYKLSWVQDNGTQDELTVEGTRANLTGWDPQKDLIVRVCVSNAVGCGPWSQPLVVSSHDRAGQQGPPHSRTS
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only