Recombinant Human VSTM1 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033222-10, PKSH033222-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: VSTM1
Target Synonym: V-set and transmembrane domain-containing protein 1; SIRL-1; Signal inhibitory receptor on leukocytes-1; VSTM1
UNIProt ID: Q6UX27
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q6UX27
Background: V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.
Sequence: Tyr17-Thr135
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 14.6 kDa
Observed MW: 25-35 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only