Recombinant Human VWFCP/ADAMTS13 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100232-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: VWFCP; ADAMTS13
Target Synonym: ADAM-TS 13; ADAMTS 13; ATS13; C9orf8; TTP; Von Willebrand factor cleaving protease; vWF CP; vWF-cleaving protease
UNIProt ID: Q76LX8
Research Areas: Signal Transduction; Cancer; Cell Biology
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: Q76LX8
Background: Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation.Zinc and calcium ions cooperatively modulate enzyme activity. The cleavage of the pro-domain is not required for protease activity. Dependence on calcium for proteolytic activity is mediated by the high affinity site.
Sequence: Thr 1151-Thr 1427
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 30.36 kDa
Observed MW: 31 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only