Recombinant Human XIAP protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100322-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: XIAP
Target Synonym: E3 ubiquitin-protein ligase XIAP; XIAP; Baculoviral IAP repeat-containing protein 4; IAP-like protein; Inhibitor of apoptosis protein 3; RING-type E3 ubiquitin transferase XIAP; X-linked inhibitor of apoptosis protein
UNIProt ID: P98170
Research Areas: Cancer; Cell Biology; Metabolism
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
Accession: P98170
Background: XIAP (X-chromosome linked inhibitor of apoptosis) is a member of the apoptosis (IAP) family of proteins that inhibit caspases. The BIR2 domain of XIAP inhibits caspase-3 and caspase-7. The ability of XIAP to inhibit caspases is prevented by SMAC/Diablo through binding to XIAP-BIR2 and -BIR3 domains.
Sequence: Met 1-Ser 497
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 54.56 kDa
Observed MW: 54 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only