Recombinant MLH1 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81583-50, E-AB-81583-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: MLH1
Target Synonym: COCA 2; COCA2; DNA mismatch repair protein Mlh1; FCC 2; FCC2; hMLH 1; hMLH1; HNPCC 2; HNPCC; HNPCC2; MGC5172; MLH 1; MLH1; MLH1; MutL homolog 1 (E. coli); MutL homolog 1; MutL homolog 1 colon cancer nonpolyposis type 2; MutL homolog 1; colon cancer; nonpolyposis type 2 (E. coli); MutL protein homolog 1; MutL; E. coli; homolog of; 1
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IF
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R02-2E8
UNIProt ID: P40692
Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human MLH1
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:1000-1:2000 IF 1:50-1:100
Calculated MW: 85kDa
Observed MW: 85kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only