Recombinant Mouse CD24 Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP01437-10, RP01437-20, RP01437-50, RP01437-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Mouse CD24 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn27-Gly53) of mouse CD24 (Accession #NP_033976.1) fused with a hFc tag at the C-terminus.
Alternate Names: CD24, CD24A, FLJ22950, FLJ43543, MGC75043, CD24
SWISS: P24807
GeneID: 12484
Species: Mouse
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 24, also known as signal transducer CD24 or heat stable antigen CD24 (HSA), is a mucin-type glycosylphosphatidylinositol-linked glycoprotein expressed on the surface of B-cells, differentiating neuroblasts and many tumors. It is involved in molecular adhesion and metastatic tumor spread and serve as a normal receptor for P-selectin. The CD24 / P-selectin pathway could be important in disseminating tumor cells by facilitating the interaction with platelet and endothelial cells. It has also been considered as a tumor marker. High rate of CD24 expressions have been found in epithelial ovarian cancer, breast cancer, non-small cell lung cancer, prostate cancer and pancreatic cancer.
Bio-Activity: Measured by its binding ability in a functional ELISA.Immobilized Human CD24 (Catalog: RP01437) at 2 μg/mL (100 μL/well) can bind Human Siglec10 with a linear range of 40-900ng/mL.
Source: HEK293 cells
Tag: C-hFc
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Antigen Sequence: NQTSVAPFPGNQNISASPNPSNATTRG
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only