Recombinant Mouse FGF-21 Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP01715-10, RP01715-20, RP01715-50, RP01715-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Mouse FGF-21 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr30-Ser210) of mouse FGF-21 (Accession #NP_064397.1.) fused with and a 6×His tag at the C-terminus.
Alternate Names: Fgf8c; FGF21
SWISS: Q9JJN1
GeneID: 56636
Species: Mouse
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Fibroblast growth factor 21 (FGF21), which stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. FGF21 has been shown to protect animals from diet-induced obesity when overexpressed in transgenic mice. It also lowers blood glucose and triglyceride levels when administered to diabetic rodents, suggesting it may exhibit the therapeutic characteristics necessary for effective treatment of diabetes. Treatment of animals with FGF21 results in increased energy expenditure, fat utilisation and lipid excretion. FGF21 is most abundantly expressed in the liver, and also expressed in the thymus at lower levels.
Source: HEK293 cells
Tag: C-6His
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Antigen Sequence: YPIPDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVRFLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYAS
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only