Recombinant Mouse Progranulin/PGRN/GRN Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP02801-10, RP02801-20, RP02801-50, RP02801-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Mouse Progranulin/PGRN/GRN Protein is produced by HEK293 cells system. The target protein is expressed with sequence (Thr18-Leu589) of Mouse Progranulin/PGRN/GRN(Accession #NP_032201.3) fused with His at the C-Terminus.
Alternate Names: Grn, Progranulin, PGRN, Acrogranin, Epithelin/granulin precursor, GP88, Glycoprotein 88, PC cell-derived growth factor, PCDGF, Proepithelin, PEPI
SWISS: P28798
GeneID: 14824
Species: Mouse
Purity: ≥ 90% as determined by reducing SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Granulin family members are important in normal development, wound healing, and tumorigenesis. Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth. Granulin expression inhibited Tat transactivation, and tethering experiments showed that this effect was due, at least in part, to a direct action on cyclin T1 in the absence of Tat.
Source: HEK293 cells
Tag: C-6His
Formulation: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Antigen Sequence: TQCPDGQFCPVACCLDQGGANYSCCNPLLDTWPRITSHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDPVPRPLL
Endotoxin: < 0.01 EU/μg of the protein by LAL method.
Research Use Only