Recombinant Mouse ST6GALNAC2 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSM041361-10, PKSM041361-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: ST6GALNAC2
Target Synonym: Gal-beta-1; 3-GalNAc alpha-2; 6-sialyltransferase; GalNAc alpha-2; 6-sialyltransferase II; ST6GalNAc II; Sialyltransferase 7B; SIAT7-B; II; Siat7; Siat7b; ST6GalNAc
UNIProt ID: P70277
Target Species: Mouse
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: P70277
Background: Alpha-N-acetylgalactosaminide alpha -2, 6-sialyltransferase 2, is a type-II membrane protein localized in the Golgi network and catalyzes 2, 6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis.-it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
Sequence: Ser28-Arg373
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 50mMTris, 150mMNaCl, pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 40.4 kDa
Observed MW: 45 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only