Recombinant Mouse TROP2/TACSTD2 Protein (His Tag)
Size: 50μg
Catalogue Number: PKSM041262-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: TROP2; TACSTD2
Target Synonym: Tumor-associated calcium signal transducer 2; Tacstd2; Trop2; Cell surface glycoprotein Trop-2; TROP-2; C80403; EGP-1; GA733-1; Ly97
UNIProt ID: Q8BGV3
Target Species: Mouse
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: Q8BGV3
Background: Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Sequence: Gln25-Gly270
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 28.8 kDa
Observed MW: 38-55 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only