Recombinant Prohibitin Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81601-50, E-AB-81601-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Prohibitin
Target Synonym: Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB; PHB1; Prohibitin
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Tags and Cell Markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB, IHC-P
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R07-2G1
UNIProt ID: P35232
Background: Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human Prohibitin
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:50-1:100
Calculated MW: 30 kDa
Observed MW: 30 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only