Recombinant Rat M-CSF/CSF1 Protein
Sizes: 10μg, 50μg
Catalogue Numbers: PKSR030451-10, PKSR030451-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: M-CSF; CSF1
Target Synonym: Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1
UNIProt ID: Q8JZQ0
Target Species: Rat
Expression Host: HEK293 Cells
Fusion Tag: None
Accession: Q8JZQ0
Background: Rat Macrophage colony-stimulating factor 1(MCSF, CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
Sequence: Glu33-Arg254
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 25.2 kDa
Observed MW: 25.2 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only