Recombinant Rhesus Macaque CD155/PVR/NECL5 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSQ050071-10, PKSQ050071-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: CD155; PVR; NECL5
Target Synonym: Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS
UNIProt ID: Q0MSE6
Target Species: Rhesus macaque
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: Q0MSE6
Background: Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.
Sequence: Met 1-Asn 343
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 35.4 kDa
Observed MW: 50-70 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only