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Recombinant TRIM21 Monoclonal Antibody - E-AB-81491

Recombinant TRIM21 Monoclonal Antibody - E-AB-81491

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Recombinant TRIM21 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-81491-50, E-AB-81491-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: TRIM21

Target Synonym: 52 kDa ribonucleoprotein autoantigen Ro/SS-A; 52 kDa Ro protein; 52kD Ro/SSA autoantigen; Autoantigen Ro/SSA; 52-KD; E3 ubiquitin-protein ligase TRIM21; RING finger protein 81; RNF81; Ro 52; Ro(SS-A); Ro52; RO52; Sicca syndrome antigen A; Sjoegren syndrome type A antigen; Sjogren syndrome antigen A1; Sjogren syndrome type A antigen; SS-A; SSA; SSA1: Sjogren syndrome antigen A1 (52kDa ribonucleoprotein autoantigen SS-A/Ro); TRIM21; Tripartite motif protein TRIM21; Tripartite motif-containing 21; Tripartite motif-containing protein 21

Research Areas: Epigenetics and Nuclear Signaling, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Rabbit Monoclonal

Clone No.: R01-1E8

UNIProt ID: P19474

Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.

Concentration: 300 μg/mL

Immunogen: Recombinant protein of human TRIM21

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification Method: Affinity Purified

Dilution: WB 1:500-1:1000

Calculated MW: 54kDa

Observed MW: 50kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only