Repetin rabbit pAb - ES4722

Repetin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4722-50, ES4722-100

Citations, Manuals and MSDS Available upon request.

Background: domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats., function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase., similarity:Belongs to the S100-fused protein family., similarity:Contains 2 EF-hand domains., tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.,

Alternate Name: RPTN; Repetin

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 90kD

Human Gene ID: 126638

Human SWISS Prot NO: Q6XPR3

Subcellular Location: Secreted, extracellular space, extracellular matrix.

Research Use Only