REST/NRSF Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7161-20, A7161-100
Citations, Manuals and MSDS Available upon request.
Background: This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 122kDa
Observed Molecular Weight: 150kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 5978
SWISS: Q13127
Alternate Names: WT6; XBR; HGF5; NRSF; DFNA27; GINGF5; REST/NRSF
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: REST
Research Use Only