Rev-erbAlpha (Phospho-Ser55/59) Rabbit Polyclonal Antibody - BT-AP12270

Rev-erbAlpha (Phospho-Ser55/59) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12270-20, BT-AP12270-50, BT-AP12270-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic| inflammatory and cardiovascular processes.

Research Areas: Epigenetics and nuclear signaling; Neuroscience; Signal transduction

Target Protein: NR1D1

Applications: WB

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rev-erbalpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P20393; Mouse: Q3UV55; Rat: Q63503

Synonyms: Rev-erbα;Ser55/59; Nuclear receptor subfamily 1 group D member 1; Rev-erbA-alpha; V-erbA-related protein 1; EAR-1

GeneID: Human: 9572; Mouse: 217166; Rat: 252917

Research Use Only