RFC2 Polyclonal Antibody - BT-AP07770

RFC2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07770-20, BT-AP07770-50, BT-AP07770-100

Citations, Manuals and MSDS Available upon request.

Background: RFC2 encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. RFC2 encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of RFC2 is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of RFC2 has been defined on chromosome 2.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: RFC2

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: RFC2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 39157

UniProt Accession: Human: P35250; Mouse: Q9WUK4; Rat: Q641W4

Synonyms: RFC2; Replication factor C subunit 2; Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40

GeneID: Human: 5982; Mouse: 19718; Rat: 116468

Research Use Only