RFX6 rabbit pAb - ES13408

RFX6 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13408-50, ES13408-100

Citations, Manuals and MSDS Available upon request.

Background: The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.[provided by RefSeq, Sep 2010],

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human RFX6 AA range: 264-314

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 222546

Human SWISS Prot NO: Q8HWS3

Subcellular Location: Nucleus

Research Use Only