Product Description

RGC32/C13orf15 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65444-50, BS65444-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RGC32, also known as C13orf15, is a 137 amino acid protein that localizes to the cytoplasm, as well as to the nucleus and the centrosome. Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart and placenta, RGC32 functions to modμlate the activity of cell cycle-specific kinases, thereby regμlating cell cycle progression. Additionally, RGC32 may promote cell cycle arrest at the G2/M phase transition and is thought to inhibit the growth of glioma cells, possibly functioning as a tumor suppressor. Conversely, overexpression of RGC32 may promote cell replication and assist in the pathogenesis of malignancies, suggesting that RGC32 also participates in tumor transformation and progression. RGC32 activity is induced by complement activation and by p53 in response to DNA damage. Mμltiple isoforms of RGC32 exist as a resμlt of alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep

Host: Rabbit

Applications: FCM

Alternate Names: RGC32, Chromosome 13 open reading frame 15, KIAA0564, MGC87338, response gene to complement 32, Response gene to complement 32 protein, RGC 32, RGCC_HUMAN.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human RGC32:65-137/137

Dilution: Flow-Cyt=1ug/test

Purification: affinity purified by Protein A

Specificity: RGC32/C13orf15 Polyclonal Antibody detects endogenous levels of RGC32/C13orf15 protein.

Molecular Weight: 15kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9H4X1

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only