Product Description

RGL1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60212-50, BS60212-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Ral GDS (Ral guanine nucleotide dissociation stimμlator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL1 (ral guanine nucleotide dissociation stimμlator-like 1), also known as RGL or RalGDS-like 1, is a 768 amino acid protein that is a putative GEF. Strongly expressed in brain, heart, spleen, kidney and testis, RGL1 is a downstream effector protein that is involved in Ras and Ral signaling pathways. RGL1 contains an N-terminal Ras-GEF domain and a C-terminal Ras-interacting domain that interacts with the GTP-bound form of Ras through its effector loop. Due to its similarity to Ral GDS, RGL1 may be implicated in carcinogenesis. Two isoforms exist due to alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Ral guanine nucleotide dissociation stimμlator-like 1, RalGDS-like 1, KIAA0959, RGL

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human RGL1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RGL1 polyclonal antibody detects endogenous levels of RGL1 protein.

Molecular Weight: ~ 87 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NZL6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only