RGS14 Polyclonal Antibody-BS61912

RGS14 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS61912-50, BS61912-100

Sizes: 50µl, 100µl

Swiss-Prot: O43566

Host: Rabbit

Reactivity: Human

Applications: IHC

Background: RGS domains bind directly to activated Ga subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Ga-GTP and Gbg. RGS proteins shorten the lifetime of the activated G protein. Western blot analysis shows strong expression of RGS14 as a primarily cytosolic protein restricted to brain and spleen. It is suggested that RGS14 may constitute a bridging molecule that allows cross-regulation of signaling pathways downstream from G protein-coupled receptors.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RGS14 polyclonal antibody detects endogenous levels of RGS14 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of RGS14 polyclonal antibody in paraffin-embedded human liver cancer tissue at 1:50.

Bioworld Molecular Weight: ~ 61 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Regulator of G-protein signaling 14

Immunogen: Synthetic peptide, corresponding Human RGS14.

Conjugate: Unconjugated

Modification: Unmodified