Product Description

RGS14 Polyclonal Antibody

Catalogue Numbers: BS62458-50, BS62458-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: O43566

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: RGS domains bind directly to activated Ga subunits and act as GTPase-activating proteins (GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both Ga-GTP and Gbg. RGS proteins shorten the lifetime of the activated G protein. Western blot analysis shows strong expression of RGS14 as a primarily cytosolic protein restricted to brain and spleen. It is suggested that RGS14 may constitute a bridging molecule that allows cross-regulation of signaling pathways downstream from G protein-coupled receptors.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity: RGS14 polyclonal antibody detects endogenous levels of RGS14 protein.

Extra Notes: Western blot (WB) analysis of RGS14 polyclonal antibody at 1:500 dilution
LaneA:LOVO whole cell lysate
LaneB:BV2 whole cell lysate
LaneC:PC12 whole cell lysate

Bioworld Molecular Weight: ~ 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Regulator of G-protein signaling 14

Immunogen: Synthetic peptide, corresponding to Human RGS14.

Conjugate: Unconjugated

Modification: Unmodified