RGS14 Polyclonal Antibody - RA29383

RGS14 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29383-50, RA29383-100

Citations, Manuals and MSDS Available upon request.

Background: regulator of G-protein signaling 14 (RGS14) Homo sapiens This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: RGS14; Regulator of G-protein signaling 14; RGS14

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 10636

Protein MW (KDa): 65

SWISS: O43566

Source: Rabbit

Research Use Only