Product Description

RGS7 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29387-50, RA29387-100

Citations, Manuals and MSDS Available upon request.

Background: function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G (o) -alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations.,PTM:Palmitoylated.,PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity.,similarity:Contains 1 DEP domain.,similarity:Contains 1 G protein gamma domain.,similarity:Contains 1 RGS domain.,subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity) . Interacts with 14-3-3 protein Tau and SNAP25BP.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: RGS7; Regulator of G-protein signaling 7; RGS7

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 6000

Protein MW (KDa): 65

SWISS: P49802

Source: Rabbit

Research Use Only