RGS7 rabbit pAb - ES7042

RGS7 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7042-50, ES7042-100

Citations, Manuals and MSDS Available upon request.

Background: function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G (o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations., PTM:Palmitoylated., PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity., similarity:Contains 1 DEP domain., similarity:Contains 1 G protein gamma domain., similarity:Contains 1 RGS domain., subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP.,

Alternate Name: RGS7; Regulator of G-protein signaling 7; RGS7

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human RGS7. AA range:155-204

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 65kD

Human Gene ID: 6000

Human SWISS Prot NO: P49802

Subcellular Location: Cytoplasm, cytosol. Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Interaction with PKD1 promotes location at the cell membrane (PubMed:10339594). Interaction with RGS7BP promotes location at the cell membrane (PubMed:15897264).

Research Use Only