Product Description

RHCG Polyclonal Antibody

Catalogue Numbers: BS62527-50, BS62527-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UBD6

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: RhCG (Rhesus blood group family type C glycoprotein), also known as RHGK (Rh glycoprotein kidney), PDRC2 (tumor-related protein DRC2) or SLC42A3, is a multi-pass membrane protein with three potential N-glycosylation sites that belongs to the Rh subfamily of the ammonium transporter family. Expressed in a wide variety of tissues with predominant expression in adult and fetal kidney, RhCG localizes to the apical and/or basolateral cell membrane (depending on the species) and is believed to function as a non-erythroid, bidirectional, electroneutral ammonium transporter. Specifically, RhCG is found throughout the kidney in sites such as the CNT (connecting segment), the DCT (distal convoluted tubule), the collecting duct and the ICT (initial collecting tubule), that are major contributors to renal ammonia secretion. This suggests that RhCG plays an important role in renal ammonia metabolism.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RHCG polyclonal antibody detects endogenous levels of RHCG protein.

Extra Notes: Western blot (WB) analysis of RHCG polyclonal antibody at 1:500 dilution
LaneA:A549 whole cell lysate
LaneB:Panc1 whole cell lysate
LaneC:MEF whole cell lysate

Bioworld Molecular Weight: ~ 53 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Ammonium transporter Rh type C; Rh glycoprotein kidney; Rhesus blood group family type C glycoprotein; Rh family type C glycoprotein; Rh type C glycoprotein; Tumor-related protein DRC2; RHCG; C15orf6; CDRC2; PDRC2; RHGK

Immunogen: Synthetic peptide, corresponding to Human RHCG.

Conjugate: Unconjugated

Modification: Unmodified