RHEB Polyclonal Antibody - BT-AP07814

RHEB Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07814-20, BT-AP07814-50, BT-AP07814-100

Citations, Manuals and MSDS Available upon request.

Background: RHEB (Ras homolog enriched in brain) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Research Areas: Signal Transduction

Target Protein: RHEB

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat, Cow

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: RHEB Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 20497

UniProt Accession: Human: Q15382; Mouse: Q921J2; Rat: Q62639

Synonyms: Ras homolog enriched in brain

GeneID: Human: 6009; Mouse: 19744

Research Use Only