RHG24 Polyclonal Antibody - BT-AP13731

RHG24 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13731-20, BT-AP13731-50, BT-AP13731-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.

Research Areas: Cancer; Signal transduction

Target Protein: ARHGAP24

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rho GTPase-activating protein 24

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8N264; Mouse: Q8C4V1; Rat: Q5U2Z7

Synonyms: Rho GTPase-activating protein 24;Filamin-A-associated RhoGAP;FilGAP;RAC1- and CDC42-specific GTPase-activating protein of 72 kDa;RC-GAP72;Rho-type GTPase-activating protein 24;RhoGAP of 73

GeneID: Human: 83478

Research Use Only