Product Description

RHOC Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4479-25, MB4479-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecμlar switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regμlate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Mμltiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: IHC, WB

Alternate Names: ARH9, ARHC, H9, RHOH9

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide corresponding to C terminal of human RHOC.

Dilution: WB 1:2000, IHC 1:150

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG2b

Molecular Weight: 21.8 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P08134

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only