Product Description

Rhodopsin Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91170-50, BS91170-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P08100(Human) P51489(Rat)

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC

All Applications: WB:1:500-1:1,000
IHC:1:50-1:200

Background: In aerobic respiration reactions, succinate dehydrogenase (SDH) catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. Mutations to these subunits cause mitochondrial dysfunction, corresponding to several distinct disorders. Mutations in the membrane bound components may cause hereditary paraganglioma, while SDHA mutations are associated with juvenile encephalopathy as well as Leigh Syndrome, a severe neurological disorder. Inactivating mutations in SDHB correlate with inherited, but not necessarily sporadic, cases of pheochromocytoma.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded rat retina tissue using anti-Rhodopsin antibody. Counter stained with hematoxylin.

Bioworld Molecular Weight: 39 kDa

Specificity: Rhodopsin polyclonal antibody detects endogenous levels of Rhodopsin protein.

Alternative Name: RHO, CSNBAD1, MGC138309, MGC138311, OPN 2, OPN2, opsd, OPSD, opsin 2, Opsin 2 rod pigment, Opsin-2, Opsin2, Retinitis Pigmentosa 4, Retinitis pigmentosa 4 autosomal dominant, RHO, Rhodopsin, RP 4, RP4,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified