Product Description

RHOQ Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60235-50, BS60235-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: tc10 is a small GTP-binding protein that is induced during nerve injury, where it cooperates with other Rho family members to facilitate nerve regeneration and, in particμlar, neurite elongation. tc10 is located predominantly in the plasma membrane, a property that depends both on its post-translational prenylation and on its ability to bind and hydrolyze GTP. tc10 colocalizes to actin filaments and interacts with the actin-binding and filament-forming protein, profilin. tc10 functions to regμlate cellμlar signaling to the actin cytoskeleton and processes associated with cell growth. tc10 also interacts with a similar subset of effectors for Cdc42 and is regμlated differentially by p50Rho GTPase-activating protein. Activated tc10 interacts with a variety of putative Rho family effectors, stimμlates JNK, and induces filopodial formation.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Rho-related GTP-binding protein RhoQ, Ras-like protein TC10, Ras-like protein family member 7A, RHOQ, ARHQ, RASL7A, TC10

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human RHOQ.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RHOQ polyclonal antibody detects endogenous levels of RHOQ protein.

Molecular Weight: ~ 20 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P17081

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only